Bananas and breast cancer.

Breast cancer risk: Data about the relation with breast cancer risk was provided by a pooled analysis of 7 cohorts (15), and one additional cohort (21). No associations were found.

Breast cancer mortality: No data was found.

Conclusion: No associations were found. No evidence was found for an association between bananas and breast cancer.

Author	Cohort name	Subjects	Years of follow-up	Cases	End point	Consumption of	Relative Risk (RR)	Adjustments
21) Olsen A (2003)	The Diet, Cancer and Health Cohort	23,798 postmenopausal women age 50-64. (Denmark)	1993-97 to 2000	425?	Breast cancer risk	Bananas	No single subgroup of fruits and/or vegetables was strongly associated with the incidence rate of breast cancer in this study (no data shown).	Age, time under study, parity, previous benign breast tumor surgery, education, use of hormone replacement therapy, duration of HRT use, intake of alcohol and BMI.
15) Smith-Warner SA. (2001)	Pooled Analysis of 7 Cohort Studies.	336,653	5-16	7,217?	Invasive breast cancer risk	Bananas	INCLUSION CRITERIA: 1) A published prospective study with at least 200 incident breast cancer cases. 2) Assessment of usual dietary intake. 3) A validation study of the diet assessment method or a closely related instrument. INCLUDED STUDIES (Follow-up years/No. of breast cancer cases): The Canadian National Breast Screening Study (1982-1987/419). Rohan TE, Howe GR, Friedenreich CM, Jain M, Miller AB. Dietary fiber, vitamins A, C, and E, and risk of breast cancer: a cohort study. Cancer Causes Control. 1993 Jan;4(1):29-37. Abstract The Iowa Women's Health Study (1986-1995/1130). Kushi LH, Fee RM, Sellers TA, Zheng W, Folsom AR. Intake of vitamins A, C, and E and postmenopausal breast cancer. The Iowa Women's Health Study. Am J Epidemiol. 1996 Jul 15;144(2):165-74. Full text The Netherlands Cohort Study (1986-1992/937). Verhoeven DT, Assen N, Goldbohm RA, Dorant E, van 't Veer P, Sturmans F. Vitamins C and E, retinol, beta-carotene and dietary fibre in relation to breast cancer risk: a prospective cohort study. Br J Cancer. 1997;75(1):149-55. Abstract The New York State Cohort (1980-1987/367). Graham S, Zielezny M, Marshall J, Priore R, Freudenheim J, Brasure J. Diet in the epidemiology of postmenopausal breast cancer in the New York State Cohort. Am J Epidemiol. 1992 Dec 1;136(11):1327-37. Abstract The New York University Women's Health Study (1985-1994/386). Toniolo P, Riboli E, Shore RE, Pasternacks BS. Consumption of meat, animal products, protein, and fat and risk of breast cancer: a prospective cohort study in New York. Epidemiology. 1994 Jul;5(4):391-7. Abstract The Nurses' Health Study A + B (A = 1980-1986/1023. B = 1986-1996/1638). Zhang S, Hunter DJ, Forman MR, Rosner BA, Speizer FE, Colditz GA. Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. J Natl Cancer Inst. 1999 Mar 17;91(6):547-56. Full text The Sweden Mammography Cohort (1987-1997/1318). Wolk A, Bergstrom R, Hunter D, Willet W, Ljung H, Holmberg L. A prospective study of association of monounsaturated fat and other types of fat with risk of breast cancer. Arch Intern Med. 1998 Jan 12;158(1):41-5. Full text RELATIVE RISK: No significant association: RR = 1.00 (0.93-1.08) per 100 g/day increment. P for heterogeneity in results across studies = 0.30. Menopausal status at follow-up did not modify the associations (no data shown).	Age at menarche, interaction between parity and age at birth of first child, oral contraceptive use (ever/never), history of benign breast disease, menopausal status at follow-up, postmenopausal hormone use, family history of breast cancer, smoking status (ever/never), education, BMI, BMI-menopausal status interaction, height, alcohol intake, and energy intake.

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

21) Olsen A (2003)

The Diet, Cancer and Health Cohort

23,798 postmenopausal women age 50-64.
(Denmark)

1993-97 to 2000

425?

Breast cancer risk

Bananas

No single subgroup of fruits and/or vegetables was strongly associated with the incidence rate of breast cancer in this study (no data shown).

Age, time under study, parity, previous benign breast tumor surgery, education, use of hormone replacement therapy, duration of HRT use, intake of alcohol and BMI.

15) Smith-Warner SA. (2001)

Pooled Analysis of 7 Cohort Studies.

336,653

5-16

7,217?

Invasive breast cancer risk

Bananas

INCLUSION CRITERIA:

1) A published prospective study with at least 200 incident breast cancer cases.
2) Assessment of usual dietary intake.
3) A validation study of the diet assessment method or a closely related instrument.

INCLUDED STUDIES (Follow-up years/No. of breast cancer cases):

The Canadian National Breast Screening Study (1982-1987/419).
Rohan TE, Howe GR, Friedenreich CM, Jain M, Miller AB. Dietary fiber, vitamins A, C, and E, and risk of breast cancer: a cohort study. Cancer Causes Control. 1993 Jan;4(1):29-37. Abstract
The Iowa Women's Health Study (1986-1995/1130).
Kushi LH, Fee RM, Sellers TA, Zheng W, Folsom AR. Intake of vitamins A, C, and E and postmenopausal breast cancer. The Iowa Women's Health Study. Am J Epidemiol. 1996 Jul 15;144(2):165-74. Full text
The Netherlands Cohort Study (1986-1992/937).
Verhoeven DT, Assen N, Goldbohm RA, Dorant E, van 't Veer P, Sturmans F. Vitamins C and E, retinol, beta-carotene and dietary fibre in relation to breast cancer risk: a prospective cohort study. Br J Cancer. 1997;75(1):149-55. Abstract
The New York State Cohort (1980-1987/367).
Graham S, Zielezny M, Marshall J, Priore R, Freudenheim J, Brasure J. Diet in the epidemiology of postmenopausal breast cancer in the New York State Cohort. Am J Epidemiol. 1992 Dec 1;136(11):1327-37. Abstract
The New York University Women's Health Study (1985-1994/386).
Toniolo P, Riboli E, Shore RE, Pasternacks BS. Consumption of meat, animal products, protein, and fat and risk of breast cancer: a prospective cohort study in New York. Epidemiology. 1994 Jul;5(4):391-7. Abstract
The Nurses' Health Study A + B (A = 1980-1986/1023. B = 1986-1996/1638).
Zhang S, Hunter DJ, Forman MR, Rosner BA, Speizer FE, Colditz GA. Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. J Natl Cancer Inst. 1999 Mar 17;91(6):547-56. Full text
The Sweden Mammography Cohort (1987-1997/1318).
Wolk A, Bergstrom R, Hunter D, Willet W, Ljung H, Holmberg L. A prospective study of association of monounsaturated fat and other types of fat with risk of breast cancer. Arch Intern Med. 1998 Jan 12;158(1):41-5. Full text

RELATIVE RISK:

No significant association: RR = 1.00 (0.93-1.08) per 100 g/day increment.

P for heterogeneity in results across studies = 0.30.

Menopausal status at follow-up did not modify the associations (no data shown).

Age at menarche, interaction between parity and age at birth of first child, oral contraceptive use (ever/never), history of benign breast disease, menopausal status at follow-up, postmenopausal hormone use, family history of breast cancer, smoking status (ever/never), education, BMI, BMI-menopausal status interaction, height, alcohol intake, and energy intake.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our diet
to breast cancer risk & mortality.

Bananas and breast cancer.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our dietto breast cancer risk & mortality.

Bananas and breast cancer.

Relating various aspects of our diet
to breast cancer risk & mortality.