Corn and breast cancer.

Breast cancer risk: Data about the relation with breast cancer risk was provided by a pooled analysis of 4 cohorts. No significant association was found.

Breast cancer mortality: No data was found.

Conclusion: No significant associations were found. No evidence was found for an association between corn and breast cancer.

Author	Cohort name	Subjects	Years of follow-up	Cases	End point	Consumption of	Relative Risk (RR)	Adjustments
15) Smith-Warner SA. (2001)	Pooled Analysis of 4 Cohort Studies.	194,295	5-16	4,595?	Invasive breast cancer risk	Corn	INCLUSION CRITERIA: 1) A published prospective study with at least 200 incident breast cancer cases. 2) Assessment of usual dietary intake. 3) A validation study of the diet assessment method or a closely related instrument. INCLUDED STUDIES (Follow-up years/No. of breast cancer cases): The Canadian National Breast Screening Study (1982-1987/419). Rohan TE, Howe GR, Friedenreich CM, Jain M, Miller AB. Dietary fiber, vitamins A, C, and E, and risk of breast cancer: a cohort study. Cancer Causes Control. 1993 Jan;4(1):29-37. Abstract The Iowa Women's Health Study (1986-1995/1130). Kushi LH, Fee RM, Sellers TA, Zheng W, Folsom AR. Intake of vitamins A, C, and E and postmenopausal breast cancer. The Iowa Women's Health Study. Am J Epidemiol. 1996 Jul 15;144(2):165-74. Full text The New York University Women's Health Study (1985-1994/386). Toniolo P, Riboli E, Shore RE, Pasternacks BS. Consumption of meat, animal products, protein, and fat and risk of breast cancer: a prospective cohort study in New York. Epidemiology. 1994 Jul;5(4):391-7. Abstract The Nurses' Health Study A + B (A = 1980-1986/1023. B = 1986-1996/1638). Zhang S, Hunter DJ, Forman MR, Rosner BA, Speizer FE, Colditz GA. Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. J Natl Cancer Inst. 1999 Mar 17;91(6):547-56. Full text RELATIVE RISK: No significant association: RR = 1.25 (0.99-1.58) per 100 g/day increment. P for heterogeneity in results across studies = > 0.99. Menopausal status at follow-up did not modify the associations (no data shown).	Age at menarche, interaction between parity and age at birth of first child, oral contraceptive use (ever/never), history of benign breast disease, menopausal status at follow-up, postmenopausal hormone use, family history of breast cancer, smoking status (ever/never), education, BMI, BMI-menopausal status interaction, height, alcohol intake, and energy intake.

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

15) Smith-Warner SA. (2001)

Pooled Analysis of 4 Cohort Studies.

194,295

5-16

4,595?

Invasive breast cancer risk

Corn

INCLUSION CRITERIA:

1) A published prospective study with at least 200 incident breast cancer cases.
2) Assessment of usual dietary intake.
3) A validation study of the diet assessment method or a closely related instrument.

INCLUDED STUDIES (Follow-up years/No. of breast cancer cases):

The Canadian National Breast Screening Study (1982-1987/419).
Rohan TE, Howe GR, Friedenreich CM, Jain M, Miller AB. Dietary fiber, vitamins A, C, and E, and risk of breast cancer: a cohort study. Cancer Causes Control. 1993 Jan;4(1):29-37. Abstract
The Iowa Women's Health Study (1986-1995/1130).
Kushi LH, Fee RM, Sellers TA, Zheng W, Folsom AR. Intake of vitamins A, C, and E and postmenopausal breast cancer. The Iowa Women's Health Study. Am J Epidemiol. 1996 Jul 15;144(2):165-74. Full text
The New York University Women's Health Study (1985-1994/386).
Toniolo P, Riboli E, Shore RE, Pasternacks BS. Consumption of meat, animal products, protein, and fat and risk of breast cancer: a prospective cohort study in New York. Epidemiology. 1994 Jul;5(4):391-7. Abstract
The Nurses' Health Study A + B (A = 1980-1986/1023. B = 1986-1996/1638).
Zhang S, Hunter DJ, Forman MR, Rosner BA, Speizer FE, Colditz GA. Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. J Natl Cancer Inst. 1999 Mar 17;91(6):547-56. Full text

RELATIVE RISK:

No significant association: RR = 1.25 (0.99-1.58) per 100 g/day increment.

P for heterogeneity in results across studies = > 0.99.

Menopausal status at follow-up did not modify the associations (no data shown).

Age at menarche, interaction between parity and age at birth of first child, oral contraceptive use (ever/never), history of benign breast disease, menopausal status at follow-up, postmenopausal hormone use, family history of breast cancer, smoking status (ever/never), education, BMI, BMI-menopausal status interaction, height, alcohol intake, and energy intake.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our diet
to breast cancer risk & mortality.

Corn and breast cancer.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our dietto breast cancer risk & mortality.

Corn and breast cancer.

Relating various aspects of our diet
to breast cancer risk & mortality.