Breast cancer risk: Data about the relation with breast cancer risk was provided by 3 cohorts. No associations were found.
Breast cancer mortality: No data was found.
Conclusion: No associations were found. No evidence was found for an association between onions and breast cancer.
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments | ||||||||||||||||||||||
| 26) Adebamowo CA. (2005) | The Nurses Health Study II. | 90,630 premenopausal women aged 26-46. (USA) | 8 (1991-1999) | 710 | Invasive breast cancer risk | Onions |
No association was found between flavonol-rich foods and the risk of breast cancer characterized by either estrogen or progestone receptor status or within strata of smoking status (data not shown). age at menarche, parity and age at first birth, family history of breast cancer in mother and/or sister, history of benign breast disease, oral contraceptive use, alcohol, energy, BMI, height, smoking habit, physical activity, and menopausal status. |
25) Wang L (2009) | The Women's Health Study | 38,408 female health professionals aged ≥ 45. | (USA) 11.5 | (1992-95 to 2007) 1,351? | Breast cancer incidence | Onion | Risk did not materially change with intake (data not shown). | Age, race, total energy, randomized treatment assignment, smoking, alcohol use, physical activity, postmenopausal status, hormone replacement therapy use, multivitamin use, family history of colorectal cancer, ovary cancer, or breast cancer, and intake of fruit and vegetables, fiber, folate, and saturated fat. |
7) Dorant E. (1995) | The Netherlands Cohort Study. | 62,573 women aged 55-69. | 3.3 | (1986-1989) 435 | primary breast cancer risk | (excluding in situ) Onions |
RR = 0.95 (0.61-1.47; P = 0.42) for the highest vs lowest quartile of consumption. | Amount specific data (number/day): 0: RR = 1. ≤ 0.25: RR = 1.02 (0.72-1.44). 0.25-0.5: RR = 0.87 (0.62-1.27). ≥ 0.5: RR = 0.95 (0.61-1.47). age, parity, age at menarche, age at first birth, age at menopause, artificially-induced menopause, oral contraceptive use, history of benign breast disease, breast cancer in mother, breast cancer in sister(s), alcohol consumption, Quetelet index, education, smoking status, dietary intake of viatmine C and beta-carotene. |
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