Breast cancer risk: Data about the relation with breast cancer risk was provided by a pooled analysis of 7 cohort studies. A weak protective effect was found.
Breast cancer mortality: No data was found.
Conclusion: A weak protective effect of rosaceae against breast cancer risk was found in a pooled analysis of 7 cohort studies. Items from the rosaceae family
possibly protect against breast cancer risk.
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments |
| 15) Smith-Warner SA. (2001) | Pooled Analysis of 7 Cohort Studies. | 336,653 | 5-16 | 7,217? | Invasive breast cancer risk | Rosaceae (e.g. apples, peaches) |
INCLUSION CRITERIA:
RELATIVE RISK: An inverse association: RR = 0.97 (0.94-1.00) per 100 g/day increment. P for heterogeneity in results across studies = 0.72. Menopausal status at follow-up did not modify the associations (no data shown). | Age at menarche, interaction between parity and age at birth of first child, oral contraceptive use (ever/never), history of benign breast disease, menopausal status at follow-up, postmenopausal hormone use, family history of breast cancer, smoking status (ever/never), education, BMI, BMI-menopausal status interaction, height, alcohol intake, and energy intake. |
| 10) Greenstein J (1996) | The Iowa Women's Health Study | 34,388 postmenopausal women. | 1986-93 | 1,018? | Breast cancer incidence | Rosaceae (e.g. apples, pears, peaches, strawberries) | A modest increase in breast cancer risk: RR = 1.25 (1.00-1.57) for high verus low intake. | Major breast cancer risk factors (not defined). |