Cabbages and cardiovascular disease.

Total cardiovascular disease: Data about the relation with total cardiovascular disease was provided by 1 cohort (36). No association was found between (Chinese) cabbage and CVD risk.

Coronary heart disease: Data about the relation with coronary heart disease was provided by 1 cohort (37). A significant protective effect of Chinese cabbage against IHD mortality was found among men, but not women.

Stroke: Data about the relation with stroke was provided by 2 cohorts. A significant protective effect of white cabbage against cerebrovascular disease risk was found in one cohort (7), but no association between Chinese cabbage and cerebrovascular death was found in the other one (37).

Conclusion: Some protective effects were found, but these differed among cabbage type and end point. Inconclusive evidence was found for an association between cabbages and CVD.

**Total cardiovascular disease:**
Author	Cohort name	Subjects	Years of follow-up	Cases	End point	Consumption of	Relative Risk (RR)	Adjustments
36) Takachi R. (2007)	The Japan Public Health Center-based Prospective Study (JPHC).	77,891 subjects (35,909 men 41,982 and women) aged 45-74. (Japan)	5.8 (1995-1998 to 2002)	1,386? (227 myocardial infarction, 1,159 stroke)	Risk of cardiovascular disease	Chinese cabbage, cabbage, or chingensai	Not significantly inversely associated with CVD risk (no data shown).	Age, public health center area, BMI, physical activity, smoking, alcohol, energy, screening examination, medication, and daily vitamin supplement use.

Coronary heart disease:

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

37) Iso H (2007)

The JACC Study.

39,486 men, and 54,325 women.
(Japan)

Not defined.

534 men, and
382 women.

Ischemic heart disease mortality

Chinese cabbage


Men:	Women
HR = 0.75 (0.58-0.95; P = < 0.05) for the highest vs lowest tertile of consumption. Amount specific data: < 1/w: HR = 1. 1-2/w: HR = 0.86 (0.67-1.09). ≥ 3/w: HR = 0.75 (0.58-0.95).	HR = 1.05 (0.77-1.44) for the highest vs lowest tertile of consumption. Amount specific data: < 1/w: HR = 1. 1-2/w: HR = 1.35 (0.98-1.85; P = < 0.10). ≥ 3/w: HR = 1.05 (0.77-1.44).

Age and study area.

Stroke:

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

37) Iso H (2007)

The JACC Study.

39,486 men, and 54,325 women.
(Japan)

Not defined.

1,098 men, and
919 women.

Cerebrovascular mortality

Chinese cabbage


Men:	Women
HR = 0.97 (0.82-1.16) for the highest vs lowest tertile of consumption. Amount specific data: < 1/w: HR = 1. 1-2/w: HR = 0.91 (0.76-1.09). ≥ 3/w: HR = 0.97 (0.82-1.16).	HR = 0.87 (0.72-1.05) for the highest vs lowest tertile of consumption. Amount specific data: < 1/w: HR = 1. 1-2/w: HR = 0.96 (0.79-1.16). ≥ 3/w: HR = 0.87 (0.72-1.05).

Age and study area.

7) Knekt P. (2002)

The Finnish Mobile Clinic Health Examination Cohort.

10,054 men and women.

28
(1967-1994)

806?

Cerebrovascular disease incidence

White cabbage

RR = 0.74 (0.60-0.91; P = 0.004).
No data shown, but probably for the highest vs lowest quartile of consumption.

Sex, age, geographic area, occupation, blood pressure, smoking, serum cholesterol, BMI, and diabetes.

Cardiovascular disease & Diet. A systematic review.

Literature review.

Relating various aspects of our
diet to heart disease and stroke.

Cabbages and cardiovascular disease.

Cardiovascular disease & Diet. A systematic review.

Literature review.

Relating various aspects of ourdiet to heart disease and stroke.

Cabbages and cardiovascular disease.

Relating various aspects of our
diet to heart disease and stroke.