| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments |
| 36) Takachi R. (2007) | The Japan Public Health Center-based Prospective Study (JPHC). | 77,891 subjects (35,909 men 41,982 and women) aged 45-74.
(Japan) | 5.8
(1995-1998 to 2002) | 1,386?
(227 myocardial infarction, 1,159 stroke) | Risk of cardiovascular disease | Grapes | Not significantly inversely associated with CVD risk (no data shown). | Age, public health center area, BMI, physical activity, smoking, alcohol, energy, screening examination, medication, and daily vitamin supplement use. |
| 17) Mink PJ. (2007) | The Iowa Women's Health Study. | 34,489 postmenopausal women aged 55-69.
(USa) | 16
(1986-2002) | 2,316 | Cardiovascular disease mortality | Grapes and raisins |
RR = 0.94 (0.81-1.09; P = 0.316) for the highest vs lowest tertile of consumption.
Amount specific data (servings/wk):
< 1: RR = 1.
1: RR = 0.96 (0.85-1.07).
> 1: RR = 0.94 (0.81-1.09). | Age, energy intake, marital status, education, blood pressure, diabetes, BMI, waist-to-hip ratio, physical activity, smoking, and estrogen use. |
| 10) Lin J (2007) | The Nurses' Health Study. | 66,360 women aged 34-59.
(USA) | 12
(1990-2002) | Risk of nonfatal MI: 938.
CHD death: 324. | Risk of myocardial infarction, and
CHD death | Raisins or grapes |
| Nonfatal MI | Fatal CHD |
RR = 1.13 (0.77-1.65; P = 0.93) for the highest vs lowest quartile of consumption.
Amount specific data (servings/week):
0-0.5: RR = 1.
0.6-< 2: RR = 0.96 (0.78-1.17).
2-< 5: RR = 0.91 (0.74-1.13).
≥ 5: RR = 1.13 (0.77-1.65).
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RR = 1.14 (0.56-2.35; P = 0.34) for the highest vs lowest quartile of consumption.
Amount specific data (servings/week):
0-0.5: RR = 1.
0.6-< 2: RR = 0.99 (0.70-1.40).
2-< 5: RR = 1.22 (0.87-1.72).
≥ 5: RR = 1.14 (0.56-2.35).
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Age; current smoking; parental history of myocardial infarction before age 60; history of hypertension, hypercholesterolemia, and diabetes; menopausal status; postmenopausal hormone use; use of aspirin; use of multivitamin and vitamin E supplements; BMI; physical activity; alcohol consumption; and total energy intake. |
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