Seaweed and cardiovascular disease.

CHD: Data about the relation with coronary heart disease was provided by 2 cohorts. No associations were found with IHD risk (3) or mortality (37).
Stroke: Data about the relation with stroke was provided by 1 cohort (37). A significant protective effect was found against cerebrovascular death among women.

Conclusion: A significant protective effect against cerebrovascular death was found among women, but results were limited to findings from one cohort. No evidence was found for an association between seaweed and CVD.

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

37) Iso H (2007)

The JACC Study.

43,179 men, and 59,483 women.
(Japan)

Not defined.

603 men, and
404 women.

Ischemic heart disease mortality

Seaweed (algae)


Men:	Women
HR = 0.93 (0.76-1.14) for the highest vs lowest tertile of consumption. Amount specific data: < 3/w: HR = 1. 3-4/w: HR = 1.04 (0.85-1.26). ≥ 5/w: HR = 0.93 (0.76-1.14).	HR = 0.90 (0.70-1.14) for the highest vs lowest tertile of consumption. Amount specific data: < 3/w: HR = 1. 3-4/w: HR = 1.08 (0.84-1.38). ≥ 5/w: HR = 0.90 (0.70-1.14).

Age and study area.

37) Iso H (2007)

The JACC Study.

43,179 men, and 59,483 women.
(Japan)

Not defined.

1,213 men, and
1,012 women.

Cerebrovascular mortality

Seaweed (algae)


Men:	Women
HR = 1.03 (0.90-1.18) for the highest vs lowest tertile of consumption. Amount specific data: < 3/w: HR = 1. 3-4/w: HR = 1.09 (0.95-1.26). ≥ 5/w: HR = 1.03 (0.90-1.18).	HR = 0.78 (0.67-0.90; P = < 0.01) for the highest vs lowest tertile of consumption. Amount specific data: < 3/w: HR = 1. 3-4/w: HR = 0.85 (0.73-1.00; P = < 0.05). ≥ 5/w: HR = 0.78 (0.67-0.90).

Age and study area.

3) Tanaka H (1987)

The Shibata Study.

963 men + 1,338 women aged ≥ 40.
(Japan)

7.5
(1977-1984)

Not defined.

Ischemic heart disease risk
(MI + angina pectoris + sudden death)

Seaweed (not defined)

No significant association was observed: RR = 1.09 (No 95% CI; No P-value) for intake ≥ 0.03 g/kg body weight per day.

Sex and age.

Cardiovascular disease & Diet. A systematic review.

Literature review.

Relating various aspects of our
diet to heart disease and stroke.

Seaweed and cardiovascular disease.

Cardiovascular disease & Diet. A systematic review.

Literature review.

Relating various aspects of ourdiet to heart disease and stroke.

Seaweed and cardiovascular disease.

Relating various aspects of our
diet to heart disease and stroke.