Data about squash consumption was provided by 3 cohorts. No association was found between summer squash, winter squash, yellow squash, or zucchini and
colon cancer or rectal cancer risk in 2 cohorts (6). No association was found between orange squash and colorectal cancer risk in another cohort (23).
| More information: back to literature review.|
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments |
| 23) Lin J. (2005) | The Women's Health Study. | 36,976 women aged > or = 45 years. (USA) | 10 | 223? | Colorectal cancer risk | Orange squash | Intakes of individual vegetable items were found not appreciably to be associated with colorectal cancer risk (data not shown). | age, randomized treatment assignment, BMI, family history of colorectal cancer, history of colon polyps, physical activity, smoking status, baseline aspirin use, red meat intake, alcohol consumption, total energy intake, menopausal status, baseline post-menopausal HT use, folate intake and multivitamin use. Glycemic load in the multivariate model did not change the overall results. |
| 6) Michels KB. (2000) | The Nurses' Health Study & The Health Professionals' Follow-up Study. | 88,764 women aged 34-59 and 47,325 men aged 40-75. (USA) | Women: 16 (1980-1996). Men: 10 (1986-1996) | 1,181? (937 colon cancer [368 men, 569 women], 244 rectal cancer [89 men, 155 women]) | Colorectal cancer risk | Summer squash, winter squash, yellow squash, or zucchini | Intake of individual vegetables that constitute the composite items was not appreciably associated with colon or rectal cancer risk in women or men (No data data shown). | age, family history of colorectal cancer, sigmoidoscopy, height, body mass index, pack-years of smoking, alcohol intake, physical activity, (women: menopausal status, postmenopausal hormone use,) aspirin use, vitamin supplement intake (ever use of multivitamins or vitamins A, C, or E), total caloric intake, and red meat consumption. |
| 6) Giovannucci E. (1994) | The Health Professionals Follow-up Study. | 47,949 men aged 40-75. (USA) | 1986-1992 | 205? | Colon cancer risk | Yellow squash | Of all vegetable items examined individually, none were statistically significantly related to the risk of colon cancer (no data shown). | Age, energy. |