| 9) Fan Y (2008) | The Shanghai Cohort Study | 18,244 men aged 45-64 from Shanghai City. | 20
(1986-89 to 2006) | 101? | Esophageal cancer incidence | Orange/tangerine |
HR = 0.56 (0.30-1.05; P = 0.06) for the highest vs lowest tertile of consumption.
Amount specific data (Tertiles not defined):
T1: HR = 1.
T2: HR = 0.80 (0.52-1.23).
T3: HR = 0.56 (0.30-1.05).
Dietary effects on ESCC (68 cases) were similar to those found for all esophageal cancer cases. | Age at interview, year of interview, neighborhood residence, level of education, BMI, number of years of smoking, number of drinks consumed per day, and number of years of drinking. |
| 8) Yamaji T (2008) | The JPHC Study | 38,790 men aged 45-74.
(Japan) | 7.7
(1995-98 to 2004) | 116 | Esophageal SCC risk | Citrus fruits (mandarin oranges, other oranges and 100% orange juice) |
HR = 0.78 (0.48-1.25; P = 0.21) for the highest vs lowest tertile of consumption.
Amount specific data (g/day):
10: HR = 1.
55: HR = 0.69 (0.45-1.06).
127: HR = 0.78 (0.48-1.25). | Age, PHC area, cigarette smoking and alcohol drinking. |
| 7) Freedman ND (2007) | The NIH-AARP Diet and Health Study | 490,802 (292,898 men and 197,904 women).
(USA) | 5
(1995-96 to 2000) | ESCC: 103.
EAC: 213. | Esophageal cancer incidence | Rutaceae (oranges, tangerines, tangelos, and grapefruits) |
| ESCC: | EAC: |
HR = 0.58 (0.34-0.99) for the highest vs lowest tertile of consumption.
Amount specific data (servings/1,000 calories):
0.08: HR = 1.
0.46: HR = 0.87 (0.56-1.35).
1.12: HR = 0.58 (0.34-0.99; P = 0.046).
|
HR = 0.96 (0.69-1.35) for the highest vs lowest tertile of consumption.
Amount specific data (servings/1,000 calories):
0.08: HR = 1.
0.46: HR = 0.85 (0.61-1.18).
1.12: HR = 0.96 (0.69-1.35).
|
Sex, age at entry into cohort, BMI, education, alcohol intake, cigarette-smoke-dose, vigorous physical activity, usual activity throughout the day and total energy. |
| 6) Iso H (2007) | The JACC Study. | 43,011 men, and 59,504 women.
(Japan) | Not defined. | 139 men, and
25 women. | esophageal cancer mortality | Citrus fruits (not defined) |
| Men: | Women: |
HR = 1.18 (0.73-1.89) for the highest vs lowest tertile of consumption.
Amount specific data:
< 3/w: HR = 1.
3-4/w: HR = 1.17 (0.73-1.88).
≥ 5/w: HR = 1.18 (0.73-1.89).
|
HR = 0.80 (0.30-2.11) for the highest vs lowest tertile of consumption.
Amount specific data:
< 3/w: HR = 1.
3-4/w: HR = 0.99 (0.33-2.98).
≥ 5/w: HR = 0.80 (0.30-2.11).
|
Age and study area. |
| 5) González CA (2006) | The EPIC Study | 481,518 men and women aged 35-70 from 9 European countries (excluding Norway). | 6.5
(1992-98 to 1999-2002) | 65 | Oesophagus adenocarcinoma incidence | Citrus fruit (not defined) |
HR = 0.73 (0.39-1.37; P = 0.22) for the highest vs lowest tertile of consumption.
Amount specific data (Tertiles):
T1: HR = 1.
T2: HR = 0.56 (0.30-1.03).
T3: HR = 0.73 (0.39-1.37).
Cut-points for tertiles of consumption differed among men and women.
For men: 10.68-17.43.
For women: 43.40-60.71.
Both in g/day.
Stratified by H pylori infection:
Not infected
(19 cases) | Infected
(28 cases) |
| HR = 0.71 (0.17-3.00) per 50 gram.
|
HR = 0.86 (0.40-1.86) per 50 gram.
|
Stratified by center and age. Adjusted by sex, height, weight, education, tobacco smoking, cigarette smoking intensity, work and leisure physical activity, alcohol intakt, energy intake, red meat intake and processed meat intake. |
| | |