Spinach and esophageal cancer.

Data about spinach was provided by 1 cohort. A significant protective effect was found against EAC, but no association was found with ESCC.

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

7) Freedman ND (2007)

The NIH-AARP Diet and Health Study

490,802 (292,898 men and 197,904 women).
(USA)

5
(1995-96 to 2000)

ESCC: 103.

EAC: 213.

Esophageal cancer incidence

Chenopodiaceae (raw spinach and cooked spinach)


ESCC:	EAC:
HR = 0.87 (0.52-1.45) for the highest vs lowest tertile of consumption. Amount specific data (servings/1,000 calories): 0: HR = 1. 0.18: HR = 1.15 (0.73-1.82). 0.96: HR = 0.87 (0.52-1.45).	HR = 0.66 (0.46-0.95) for the highest vs lowest tertile of consumption. Amount specific data (servings/1,000 calories): 0: HR = 1. 0.18: HR = 0.91 (0.67-1.24). 0.96: HR = 0.66 (0.46-0.95; P = 0.023).

Sex, age at entry into cohort, BMI, education, alcohol intake, cigarette-smoke-dose, vigorous physical activity, usual activity throughout the day and total energy.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our diet
to esophageal cancer risk & mortality.

Spinach and esophageal cancer.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our dietto esophageal cancer risk & mortality.

Spinach and esophageal cancer.

Relating various aspects of our diet
to esophageal cancer risk & mortality.