Lung cancer risk: Data about lung cancer risk was provided by 3 publications of The EPIC Study. No association was found.
Lung cancer mortality: Data about lung cancer mortality was provided by 1 cohorts which is part of The EPIC Study. No association was found.
Conclusion: No evidence was found for an association between allium vegetables and lung cancer.
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments |
| 19) Linseisen J (2007) | The EPIC Study | 478,590 individuals, mostly aged 25-70 from 10 European countries. | 6.4 (1992-2000) | 1,126? (608 men, 518 women), of which 731 current smokers, 291 former smokers, and 98 never smokers) | lung cancer risk | Onions and garlic | not related to lung cancer (no data shown) | adjusted for tobacco smoking (status and duration), education (5 categories), physical activity at work (5 categories), intake of red meat, intake of processed meat, height, weight, nonfat energy intake, energy intake from fat, ethanol intake at baseline. |
| 19) Miller AB (2004) | The EPIC Study. | 335,376 individuals, mostly aged 25-70 from 7 European countries (excluding Germany, France and Greece) | 1992-98 to 1998-2002 | 860? (532 smokers, 236 ex-smokers, and 88 never smokers) | lung cancer risk | Onions and garlic | There was no association (no data shown). | Smoking, height and stratified by sex and centre. |
| 19) Miller AB (2002) | The EPIC Study | 127,892 men and 289,946 women. | 4 | 247? men and 245? women | Lung cancer incidence | Onion and garlic | No significant association with lung cancer (no data shown). | Stratified by centre and gender and adjusted for time of follow-up and smoking. |
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments |
| 19) Skuladottir H (2006) | The Danish Diet, Cancer and Health Study. | 286 currently smoking men and women with lung cancer. | (1993-97 to 2004) | Not defined | Lung cancer mortality | Allium vegetables (onion and garlic) |
HR = 0.94 (0.62-1.43; No P-value) for the highest vs lowest tertile of consumption. Amount specific data (Tertiles not defined): T1: HR = 1. T2: HR = 1.06 (0.73-1.53). T3: HR = 0.94 (0.62-1.43). | Sex, extend of disease, duration of smoking, fruit, potatoes. Leafy, fruiting, root, cabbages, and stalk vegetables. |