Lung cancer risk: Data about lung cancer risk was provided by a pooled analysis of 7 studies (24) and one additional study (29). No associations were found of
high vs low consumption.
Lung cancer mortality: No data was found.
Conclusion: No evidence was found for an association between bananas and lung cancer.
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments | ||||||||||||||||||||||||||||||||||||||||||||||||
| 29) Wright ME (2008) | The NIH-AARP Diet and Health Study | 472,081 subjects (281,288 men and 190,793 women) aged 50-71. (USA) | 8 (1995-2003) | See variables | Lung cancer risk | Musaceae (bananas) |
All men (3,834 cases): RR = 0.97 (0.87-1.08; P = 0.42) for the highest vs lowest quintile of consumption. Amount specific data (servings per 1000 kcal per day): 0.01: RR = 1. 0.05: RR = 1.00 (0.91-1.09). 0.14: RR = 0.97 (0.88-1.07). 0.29: RR = 0.94 (0.85-1.04). 0.53: RR = 0.97 (0.87-1.08).
All women (2,201 cases): RR = 1.01 (0.88-1.15; P = 0.73) for the highest vs lowest quintile of consumption. Amount specific data (servings per 1000 kcal per day): 0.01: RR = 1. 0.07: RR = 0.98 (0.86-1.10). 0.18: RR = 0.80 (0.70-0.91). 0.35: RR = 0.94 (0.83-1.08). 0.63: RR = 1.01 (0.88-1.15). In analyses stratified by histological type, notable inverse associations were observed between squamous cell carcinoma and intakes of musaceae among women (RR = 0.66; 95% CI = 0.45-0.96; P = 0.02).
One serving of fruits = 1 medium sized fresh fruit, 1/2 cup of chopped fruit, or 6 ounces of fruit juice. Age, energy intake, race, education, BMI, smoking status, smoking dose, time since quitting, alcohol intake, physical activity, and family history of any cancer. |
24) Smith-Warner SA (2003) | Pooled analysis of 7 prospective studies. | 399,765 | 6-16 | 3,112 | Lung cancer risk | Bananas |
INCLUSION CRITERIA: |
INCLUDED STUDIES (Follow-up years/No. of lung cancer cases):
RELATIVE RISK: RR = 1.04 (0.89-1.22; P = 0.61) for the highest vs lowest quartile of consumption. Amount specific data (servings): 0: RR = 1. > 0 to < 1/week: RR = 0.97 (0.86-1.10). > 1/week to 1/2/day: RR = 0.90 (0.80-1.02). ≥ 1/2/day: RR = 1.04 (0.89-1.22). One serving = 1 banana. P for between-study heterogeneity: 0.74. P for between-study heterogeneity due to sex: 0.32. Adjusted for education, BMI, alcohol intake, calories, smoking status, smoking duration for past/current smokers, amount smoked for current smokers. |
14) Feskanich D (2000) | The Nurses' Health Study | & The Health Professionals' Follow-up Study 77,283 US women (38-63 years) and 47,778 men (40-75 years) | Women: 1984-1996. | Men: 1986-1996. 516? women, and | 258? men Total lung cancer risk | Bananas | No significant association with risk (no data shown). | Not defined, but probably: age, follow-up cycle, smoking status,years since quitting among past smokers, cigarettes smoked/day among current smokers, age at start of smoking, total energy intake, and availability of diet data after baseline measure. |
14) Speizer FE (1999) | The Nurses' Health Study. | 89,284 women aged 34-59 years. | (USA) 12 | (1980-1992) 399? | Lung cancer risk | Bananas |
RR = 1.0 (No 95% CI; P = 0.77) for the highest vs the lowest quintile of consumption. | Amount specific data (Frequency of consumption): Never: RR = 1. 1-3/mo: RR = 0.9. 2-4/wk: RR = 0.8. 5-6/wk: RR = 1.0. ≥ 1/day: RR = 1.0. age, smoking (past, current, amount in 1980), and age of starting to smoke |
11) Voorrips LE (2000) | The Netherlands Cohort Study | 62,573 women and 58,279 men aged 55-69. | 6.3 | (1986-1992) 963 | lung cancer risk | Bananas |
RR = 0.8 (0.7-1.1; P = 0.03) for the highest vs lowest tertile of consumption. | Amount specific data (g/day): 0: RR = 1. 4: RR = 0.9 (0.7-1.1). 32: RR = 0.8 (0.7-1.1). Additional adjustment for total vegetable intake did not change results at all (No data shown). age, sex, family history of lung cancer, highest educational level, current smoker, years of smoking, number of cigarettes/day and total fruit intake. |
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