| 29) Wright ME (2008) | The NIH-AARP Diet and Health Study | 472,081 subjects (281,288 men and 190,793 women) aged 50-71.
(USA) | 8
(1995-2003) | See variables | Lung cancer risk | Solanaceae (tomatoes, peppers) |
All men (3,834 cases):
RR = 1.02 (0.93-1.13; P = 0.60) for the highest vs lowest quintile of consumption.
Amount specific data (servings per 1000 kcal per day):
0.07: RR = 1.
0.15: RR = 0.97 (0.88-1.07).
0.23: RR = 0.98 (0.89-1.08).
0.34: RR = 0.94 (0.85-1.03).
0.60: RR = 1.02 (0.93-1.13).
Men. Stratified by smoking status:
Never smokers
(141? cases) | Former smokers
(2,110? cases) | Current smokers
(1,583? cases) |
| RR = 1.59 (0.94-2.70; P = 0.10) for the highest vs lowest quintile of consumption.
|
RR = 1.00 (0.87-1.14; P = 0.50) for the highest vs lowest quintile of consumption.
|
RR = 1.04 (0.90-1.22; P = 0.26) for the highest vs lowest quintile of consumption.
|
All women (2,201 cases):
RR = 1.11 (0.97-1.27; P = 0.04) for the highest vs lowest quintile of consumption.
Amount specific data (servings per 1000 kcal per day):
0.08: RR = 1.
0.17: RR = 0.98 (0.86-1.11).
0.27: RR = 1.00 (0.87-1.14).
0.40: RR = 1.04 (0.91-1.19).
0.71: RR = 1.11 (0.97-1.27).
Women. Stratified by smoking status:
Never smokers
(170? cases) | Former smokers
(835? cases) | Current smokers
(1,196? cases) |
| RR = 0.82 (0.51-1.33; P = 0.74) for the highest vs lowest quintile of consumption.
|
RR = 1.08 (0.87-1.34; P = 0.26) for the highest vs lowest quintile of consumption.
|
RR = 1.17 (0.98-1.40; P = 0.06) for the highest vs lowest quintile of consumption.
|
One serving of vegetables = 1 cup of raw, leafy vegetables, 1/2 cup of other vegetables, or 6 ounces of juice.Age, energy intake, race, education, BMI, smoking status, smoking dose, time since quitting, alcohol intake, physical activity, and family history of any cancer. |
| 22) Neuhouser ML (2003) | The Beta-carotene And Retinol Efficacy Trial (CARET) (2003) | 14,120 current or former heavy smokers (male/female) and asbestos-exposted workers (male) aged 50-69. | 12
(1989-2001) | 742?
(326 in placebo arm, and 414 in intervention arm) | Primary lung cancer risk | Solanaceae (potatoes (including French fries; boiled, mashed, and baked potatoes), tomatoes, tomato juice, and mixed foods and condiments with tomatoes) |
Intervention arm (daily combination of 30 mg of beta carotene and 25,000 IU of retinyl palmitate):
(n = 7072) | Placebo arm:
(n = 7048) |
RR = 0.98 (0.70-1.37; P = 0.72) for the highest vs lowest quintile of consumption.
Amount specific data (servings/week):
≤ 3.3: RR = 1.
3.4-5.3: RR = 0.93 (0.69-1.26).
5.4-7.4: RR = 1.01 (0.74-1.36).
7.5-10.3: RR = 0.85 (0.62-1.18).
≥ 10.4: RR = 0.98 (0.70-1.37).
|
RR = 1.36 (0.94-2.03; P = 0.16) for the highest vs lowest quintile of consumption.
Amount specific data (servings/week):
≤ 3.3: RR = 1.
3.4-5.3: RR = 1.18 (0.83-1.68).
5.4-7.4: RR = 1.09 (0.75-1.57).
7.5-10.3: RR = 1.16 (0.79-1.69).
≥ 10.4: RR = 1.38 (0.94-2.03).
|
Sex, age, smoking status, total pack-years of smoking, asbestos exposure, race-ethnicity, enrollment center, and total vegetables. |
| |