Melons/cantaloupe and ovarian cancer.

Ovarian cancer risk: Data about the relation between cantaloupes and ovarian cancer risk was provided by a pooled analysis of 7 cohorts. No association was found.

Ovarian cancer mortality: No data was found.

Conclusion: No associations were found. No evidence was found for an association between cantaloupes and ovarian cancer.

Author	Cohort name	Subjects	Years of follow-up	Cases	End point	Consumption of	Relative Risk (RR)	Adjustments
9) Koushik A (2005)	Pooled analysis of 7 cohort studies.	318,480 women.	9-16	1,149	Invasive epithelial ovarian cancer risk	Cantaloupe	INCLUSION CRITERIA: At least 50 incident invasive epithelial ovarian cancer cases. An assessment of usual diet. A validation study of the diet assessment method or a closely related instrument. INCLUDED STUDIES (Follow-up years/No. of ovarian cancer casses): The Breast Cancer Detection Demonstration Project (1987-1999/142). Hannan LM. Physical activity and risk of ovarian cancer: a prospective cohort study in the United States. Cancer Epidemiol Biomarkers Prev. 2004 May;13(5):765-70. Full text The Cancer Prevention Study II Nutrition Cohort (1992-2001/278). Calle EE. The American Cancer Society Cancer Prevention Study II Nutrition Cohort: rationale, study design, and baseline characteristics. Cancer. 2002 Jan 15;94(2):500-11. Abstract The Iowa Women's Health Study (1986-2001/208). Kushi LH. Prospective study of diet and ovarian cancer. Am J Epidemiol. 1999 Jan 1;149(1):21-31 Full text The New York University Women's Health Study (1985-1998/65). Kato I. Prospective study of diet and female colorectal cancer: the New York University Women's Health Study. Nutr Cancer. 1997;28(3):276-81. Abstract The Nurses' Health Study B (1986-2002/315). Fairfield KM. Risk of ovarian carcinoma and consumption of vitamins A, C, and E and specific carotenoids: a prospective analysis. Cancer. 2001 Nov 1;92(9):2318-26. Full text The Nurses' Health Study II (1991-2000/52). Cho E. Premenopausal fat intake and risk of breast cancer. J Natl Cancer Inst. 2003 Jul 16;95(14):1079-85. Full text The Women's Health Study (1993-2004/104). Higginbotham S. Dietary glycemic load and breast cancer risk in the Women's Health Study. Cancer Epidemiol Biomarkers Prev. 2004 Jan;13(1):65-70. Full text RELATIVE RISK: RR = 1.55 (0.77-3.10) for a daily increment of 1 serving (= 1/4 melon, or 134 g). P for between-studies heterogeneity = 0.05.	Parity, oral contraceptive use, menopausal status and postmenopausal hormone use, age at menarche, BMI, physical activity, smoking status, and total energy intake. Age in years and year of questionnaire return were included as stratification variables.

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

9) Koushik A (2005)

Pooled analysis of 7 cohort studies.

318,480 women.

9-16

1,149

Invasive epithelial ovarian cancer risk

Cantaloupe

INCLUSION CRITERIA:

At least 50 incident invasive epithelial ovarian cancer cases.
An assessment of usual diet.
A validation study of the diet assessment method or a closely related instrument.

INCLUDED STUDIES (Follow-up years/No. of ovarian cancer casses):

The Breast Cancer Detection Demonstration Project (1987-1999/142).
Hannan LM. Physical activity and risk of ovarian cancer: a prospective cohort study in the United States. Cancer Epidemiol Biomarkers Prev. 2004 May;13(5):765-70. Full text
The Cancer Prevention Study II Nutrition Cohort (1992-2001/278).
Calle EE. The American Cancer Society Cancer Prevention Study II Nutrition Cohort: rationale, study design, and baseline characteristics. Cancer. 2002 Jan 15;94(2):500-11. Abstract
The Iowa Women's Health Study (1986-2001/208).
Kushi LH. Prospective study of diet and ovarian cancer. Am J Epidemiol. 1999 Jan 1;149(1):21-31 Full text
The New York University Women's Health Study (1985-1998/65).
Kato I. Prospective study of diet and female colorectal cancer: the New York University Women's Health Study. Nutr Cancer. 1997;28(3):276-81. Abstract
The Nurses' Health Study B (1986-2002/315).
Fairfield KM. Risk of ovarian carcinoma and consumption of vitamins A, C, and E and specific carotenoids: a prospective analysis. Cancer. 2001 Nov 1;92(9):2318-26. Full text
The Nurses' Health Study II (1991-2000/52).
Cho E. Premenopausal fat intake and risk of breast cancer. J Natl Cancer Inst. 2003 Jul 16;95(14):1079-85. Full text
The Women's Health Study (1993-2004/104).
Higginbotham S. Dietary glycemic load and breast cancer risk in the Women's Health Study. Cancer Epidemiol Biomarkers Prev. 2004 Jan;13(1):65-70. Full text

RELATIVE RISK:

RR = 1.55 (0.77-3.10) for a daily increment of 1 serving (= 1/4 melon, or 134 g).

P for between-studies heterogeneity = 0.05.

Parity, oral contraceptive use, menopausal status and postmenopausal hormone use, age at menarche, BMI, physical activity, smoking status, and total energy intake. Age in years and year of questionnaire return were included as stratification variables.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our diet
to ovarian cancer risk & mortality.

Melons/cantaloupe and ovarian cancer.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our dietto ovarian cancer risk & mortality.

Melons/cantaloupe and ovarian cancer.

Relating various aspects of our diet
to ovarian cancer risk & mortality.