Root vegetables and pancreatic cancer.
Data about root vegetables was provided by 2 cohorts. No significant associations were found with pancreatic cancer risk.
Data about root vegetables was provided by 2 cohorts. No significant associations were found with pancreatic cancer risk.
| Author | Cohort name | Subjects | Years of follow-up | Cases | End point | Consumption of | Relative Risk (RR) | Adjustments |
| 18) Vrieling A (2009) | The EPIC Study | 478,400 subjects from 10 European countries. | 8.9 (1991-2000 to 2002-2007) | 555 | Invasive exocrine pancreatic cancer incidence | Root vegetables (not defined) |
HR = 0.77 (0.59-1.01; P = 0.08) for the highest vs lowest quartile of consumption. Amount specific data (g/day): < 7: HR = 1. 7-17: HR = 0.90 (0.71-1.14). 17-39: HR = 0.88 (0.69-1.13). > 39: HR = 0.77 (0.59-1.01). | Stratified by age at entry, sex and center. Adjusted for energy from fat, energy from non-fat, weight, height, history of diabetes, and smoking status. Waist-to-hip ratio, alcohol, red meat and processed meat intake, and education did not markedly change the risk estimates. |
| 6) Stolzenberg-Solomon RZ (2002) | The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC). | 27,111 male smokers of ≥ 5 cigarettes/day aged 50-69. (Finland) | 13 (1985-88 to 1997) | 163? | Primary malignant neoplasm of the exocrine pancreas incidence | Root vegetables (not defined) |
HR = 0.69 (0.42-1.14; P = 0.34) for the highest vs lowest quintile of consumption. Amount specific data (g/day): ≤ 8.5: HR = 1. > 8.5 and ≤ 15.6: HR = 0.82 (0.50-1.33). > 15.6 and ≤ 24.6: HR = 0.90 (0.56-1.45). > 24.6 and ≤ 38.8: HR = 1.03 (0.66-1.63). > 38.8: HR = 0.69 (0.42-1.14). | Energy intake, age and years of smoking. Additional variables examined in the analyses included ATBC trial interventions; dietary folate, saturated fat, and carbohydrate intakes; history of diabetes mellitus; occupational physical activity; and education. |