Citrus fruit and prostate cancer.
Total prostate cancer risk: Data about total prostate cancer risk was provided by 3 cohorts, including a total of 4,705 cases.
In one cohort an increased cancer risk was found among white men, but not among men of other ethnic groups (17). And in one other cohort, existing
predominantly of white men, a significantly increased risk was found as well (10). No association was found in the smallest cohort (1).
Advanced prostate cancer risk: Data about the relation with advanced prostate cancer risk was provided by one cohort (10). No association
was found with poorly/undifferentiated cancer risk.
Prostate cancer mortality: Data about the relation with prostate cancer mortality was provided by one cohort (20). A nonsignificantly increased trend of
mortality risk was found.
Conclusion: A significantly increased risk of total prostate cancer was found among white men in 2 cohorts of moderate-large size, and no other
effects were found among white men. Citrus fruit possibly increases total prostate cancer risk among white men.
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