| 18) Kirsh VA. (2007) | The screening arm of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. | 29,361 men aged 55-74.
(USA) | mean 4.2
(1993-2001) | 1,338
of which 520 aggressive (Stage III-IV or gleason score ≥ 7), and ? extraprostatic (Stage III-IV only) | prostate cancer risk | Onions | No association either overall or by disease group (aggressive/extraprostetic cancer).
Prostate cancer risk:
RR = 1.01 (0.88-1.17; P = 0.88) for the highest vs lowest quartile of consumption.
Amount specific data (servings/wk):
< 1: RR = 1.
1: RR = 1.08 (0.91-1.28).
2: RR = 0.98 (0.84-1.15).
> 2: RR = 1.01 (0.88-1.17). | age, total energy, race, study center, family history of prostate cancer, BMI, smoking status, physical activity, supplemental vitamine E intake, total fat intake, red meat intake, diabetes, aspirin use, and previous number of prostate cancer screening examinations during the follow-up period.
Results were not statistically significantly altered by additional adjustment for total fruit or vegetable intake (as appropriate) and tomato intake or for history of PSA tests before study enrollment. |
| 10) Schuurman AG (1998) | The Netherlands Cohort Study. | 58,279 men aged 55-69 | 6.3
((1986-1992) | 606? | prostate cancer risk | Onions | No association: RR = 0.93 (0.79-1.10) per 25 g/day increment. | age, family history of prostate cancer, socioeconomic status and total fruit.
Additionaly adjusted for total vegetables. |