Raw vegetables and prostate cancer.

Total prostate cancer risk: Data about the relation between raw vegetables and prostate cancer risk was provided by 2 cohorts. No associations were found.
Advanced prostate cancer risk: Data about the relation with advanced prostate cancer risk was provided by one cohort (10). No association was found with poorly or undifferentiated prostate cancer risk.
Prostate cancer mortality: No data was found.

Conclusion: No evidence was found for an association between raw vegetables and prostate cancer.

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Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

10) Schuurman AG (1998)

The Netherlands Cohort Study.

58,279 men aged 55-69

6.3
((1986-1992)

606
(181 well differentiated, 217 moderately differentiated, and 153 poorly- or undifferentiated)

prostate cancer risk

Raw vegetables

RR = 0.96 (0.69-1.37; P = 0.61) for the highest vs lowest quintile of consumption.

Amount specific data (g/day):
7.0: RR = 1.
19.0: RR = 0.89 (0.64-1.23).
30.0: RR = 0.97 (0.71-1.34).
44.0: RR = 1.11 (0.81-1.51).
73.0: RR = 0.96 (0.69-1.34).

**Prostate cancer risk in subgroups on differentiation grade. RRs are per 25 g/day increment**
well differentiated	moderately differentiated	poorly or undifferentiated
RR = 1,12 (0.94-1.34)	RR = 1.03 (0.87-1.22)	RR = 0.93 (0.76-1.13)

RRs between subgroups of tumor sizes did not differ to a large extent and were mostly around the null value; the same applied to latent and nonlatent tumors (data not shown).

age, family history of prostate cancer, socioeconomic status and total fruit.
The RR per 25 g/day increment is additionaly adjusted for total vegetables.

6) Le Marchand L (1994)

No cohort name.

20,316 men of various ethnicities aged ≥ 45.

1975-80 to 1989

198?

Invasive prostate cancer risk

Raw vegetables (not defined)

RR = 1.1 (0.7-1.7; P = 0.69) for the highest vs lowest quartile of consumption.

Amount specific data (gm/week):
82: RR = 1.
Not defined: RR = 1.1 (0.7-1.7).
Not defined: RR = 1.1 (0.7-1.7).
302: RR = 1.1 (0.7-1.7).

Age, ethnicity, and income.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our diet
to prostate cancer risk & mortality.

Raw vegetables and prostate cancer.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our dietto prostate cancer risk & mortality.

Raw vegetables and prostate cancer.

Relating various aspects of our diet
to prostate cancer risk & mortality.