Seaweed and prostate cancer.

Prostate cancer risk: Data about the relation between seaweed and prostate cancer risk was provided by 2 cohorts.
A significantly increased risk was found in one cohort (3), but no association with risk was found in the other cohort (14).
Prostate cancer mortality: Data about the relation with prostate cancer mortality was provided by one cohort (20). No association was found.

Conclusion: Inconsistent findings were done. Inconclusive evidence was found for an association between seaweed and prostate cancer.

| More information: back to literature review.|

Author	Cohort name	Subjects	Years of follow-up	Cases	End point	Consumption of	Relative Risk (RR)	Adjustments
20) Iso H (2007)	The JACC Study.	43,179 men. (Japan)	Not defined.	159	Prostate cancer mortality	Seaweed (algae)	HR = 0.91 (0.61-1.35) for the highest vs lowest tertile of consumption. Amount specific data: < 3/w: HR = 1. 3-4/w: HR = 1.17 (0.80-1.71). ≥ 5/w: HR = 0.91 (0.61-1.35).	Age and study area.
14) Allen NE (2004)	The Hiroshima/Nagasaki Life Span Study.	18,115 men. (Japan)	mean 16.9 (1963-1996)	193	Prostate cancer risk	Seaweed	RR = 0.86 (0.60-1.24; P = 0.38) for the highest vs lowest tertile of consumption. Amount specific data (times/week): < 2: RR = 1. 2-4: RR = 0.74 (0.53-1.03). Almost daily: RR = 0.86 (0.60-1.24).	age, calendar period, city of residence, ratiation dose and education level
3) Severson RK (1989)	The Japan-Hawaii Cancer Study.	7999 men of Japanese ancestry.	18-21 (1965-68 to 1986)	174	Prostate cancer risk	Nori, kobu, other seaweeds	RR = 1.74 (1.05-2.90; P = 0.017) for the highest vs lowest tertile of consumption. Amount specific data (times): ≤ 1/wk: RR = 1. 2-4/wk: RR = 1.32 (0.89-1.96). ≥ 1/wk: RR = 1.74 (1.05-2.90).	Age.

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

20) Iso H (2007)

The JACC Study.

43,179 men.
(Japan)

Not defined.

159

Prostate cancer mortality

Seaweed (algae)

HR = 0.91 (0.61-1.35) for the highest vs lowest tertile of consumption.

Amount specific data:
< 3/w: HR = 1.
3-4/w: HR = 1.17 (0.80-1.71).
≥ 5/w: HR = 0.91 (0.61-1.35).

Age and study area.

14) Allen NE (2004)

The Hiroshima/Nagasaki Life Span Study.

18,115 men.
(Japan)

mean 16.9
(1963-1996)

193

Prostate cancer risk

Seaweed

RR = 0.86 (0.60-1.24; P = 0.38) for the highest vs lowest tertile of consumption.

Amount specific data (times/week):
< 2: RR = 1.
2-4: RR = 0.74 (0.53-1.03).
Almost daily: RR = 0.86 (0.60-1.24).

age, calendar period, city of residence, ratiation dose and education level

3) Severson RK (1989)

The Japan-Hawaii Cancer Study.

7999 men of Japanese ancestry.

18-21
(1965-68 to 1986)

174

Prostate cancer risk

Nori, kobu, other seaweeds

RR = 1.74 (1.05-2.90; P = 0.017) for the highest vs lowest tertile of consumption.

Amount specific data (times):
≤ 1/wk: RR = 1.
2-4/wk: RR = 1.32 (0.89-1.96).
≥ 1/wk: RR = 1.74 (1.05-2.90).

Age.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our diet
to prostate cancer risk & mortality.

Seaweed and prostate cancer.

Cancer & Diet. A systematic review.

Literature review.

Relating various aspects of our dietto prostate cancer risk & mortality.

Seaweed and prostate cancer.

Relating various aspects of our diet
to prostate cancer risk & mortality.