Tomatoes and all-cause mortality/survival.

Data about tomatoes was provided by 3 cohorts. A significant and strong protective effect was found in one cohort examining small children (5), but no association was found among adults in the other cohorts (1, 32).

Conclusion: A significant protective effect was found in one cohort only. No evidence was found for an association between tomatoes and mortality.

Author

Cohort name

Subjects

Years of follow-up

Cases

End point

Consumption of

Relative Risk (RR)

Adjustments

32) Iso H (2007)

The JACC Study.

41,547 men, and 56,947 women.
(Japan)

Not defined.

8,736 men, and
6,099 women.

Mortality from all causes

Tomatoes


Men:	Women
HR = 0.96 (0.91-1.02) for the highest vs lowest tertile of consumption. Amount specific data: < 1/w: HR = 1. 1-2/w: HR = 0.96 (0.91-1.02). ≥ 3/w: HR = 0.96 (0.91-1.02).	HR = 0.98 (0.92-1.05) for the highest vs lowest tertile of consumption. Amount specific data: < 1/w: HR = 1. 1-2/w: HR = 0.95 (0.89-1.02). ≥ 3/w: HR = 0.98 (0.92-1.05).

Age and study area.

5) Fawzi W (2000)

No cohort name defined.

28,753 children 6-60 months old who were free of vitamin A deficiency.
(Sudan)

18 months
(1988-?)

232

Death

Tomatoes (either raw or as part of a cooked meal)

Background: Each household was visited every 6 mo for a maximum of 3 visits. Tomato consumption was assessed at each visit. Mothers recalled whether a child had consumed tomatoes in the previous 24 h.

RR = 0.20 (0.05-0.84; P = 0.0002) for the highest vs lowest quartile of consumption.

Amount specific data (Consumption frequency [at no. of visits]):
0: RR = 1.
1: RR = 0.62 (0.43-0.89).
2: RR = 0.60 (0.34-1.05).
3: RR = 0.20 (0.05-0.84).

Age, sex, vitamin A supplements, wealth, maternal literacy, water in house, region, morbidity, nutritional status, and seasonality.

1) Fraser GE (1997)

The Adventist Health Study

1.668 black California men and women aged ≥ 25.

1976-1985

See variables

All-cause mortality

Tomatoes (fresh or canned)


Both sexes (153? cases)	Men (73? cases)	Women (80? cases)
HR = 0.9 (0.5-1.6) for the highest vs lowest tertile of consumption. Amount specific data (Frequency of use in times/week): < 1: HR = 1. 1-4: HR = 1.0 (0.6-1.6). ≥ 5: HR = 0.9 (0.5-1.6).	HR = 0.9 (0.4-2.2) for the highest vs lowest tertile of consumption. Amount specific data (Frequency of use in times/week): < 1: HR = 1. 1-4: HR = 1.3 (0.6-2.6). ≥ 5: HR = 0.9 (0.4-2.2).	HR = 0.9 (0.4-2.1) for the highest vs lowest tertile of consumption. Amount specific data (Frequency of use in times/week): < 1: HR = 1. 1-4: HR = 0.8 (0.4-1.5). ≥ 5: HR = 0.9 (0.4-2.1).

Age, smoking and exercise.

Mortality & Diet.

A systematic review.

Literature review

Relating various aspects of our
diet to mortality & survival.

Tomatoes and all-cause mortality/survival.

Mortality & Diet.

A systematic review.

Literature review

Relating various aspects of ourdiet to mortality & survival.

Tomatoes and all-cause mortality/survival.

Relating various aspects of our
diet to mortality & survival.